science-softCon uv/vis+ spectra data base;	www.uv-spectra.de; (C) science-softCon 2016

Substance: camptothecin			Other Names: (S-)4-Ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]chinolin- 3,14-(4H,12H)-dion

Formula: 	C20H16N2O4			CAS-No.: 7689-03-4	PubChem: 24360

Study: UV absorption spectra

                
Authors: N. Sanna, G. Chillemi, L. Gontrani, A. Grandi, G. Mancini, S. Castelli, G. Zagotto, C. Zazza, V. Barone, A. Desideri

Title: UV-Vis Spectra of the Anticancer Campothecin Family Drugs in Aqueous Solution: Specific Spectroscopic Signatures Unraveled 
by a Combined Computational and Experimental Study

Journal/Source: J. Phys. Chem. B, 113 (16), 5369-5375, (2009); DOI: 10.1021/jp809801y


Data: table, diagram

Energy/Wavelength range: 225 - 500 nm

Resolution: 

Temperature: 298 K

Temperature dependence: no

Pressure/Concentration: 1.2 µM

Phase: aqueous solution (acetate buffer)

pH: 5.0


Comments: UV-vis experimental absorption spectrum of 1.2 µM CPT at pH 5.0 in acetate buffer and in the 225-500 nm region. The three most 
intense band maxima are at 369, 354, and 334 nm.

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